Both movies have to do with young female protagonist approaching her thirties, still finding herself, and figuring out what she wants out of life including her love life.
Both of these movies star Yuki Furukawa and Ryunosuke Kamiki. In addition, they have similar style of humor, although "Murder at Shujinsou" is definitely more o a zany comedy that "Poison Berry in My Brain."
Both titles are about a woman who is in her early thirties worry about the direction her life needs to go. Marriage, career, and dead-end relationships are common themes and worries for the main women.